Rejuran Healer (Salmon DNA / PN Injection)
Rejuran, Salmon DNA injection, PN injection, PDRN, Polynucleotide injection
tag:Inner Dryness, Skin Recovery
If your skin's been looking dull and rough lately, this one's worth trying. Don't expect a dramatic overnight change — but after about 3 sessions, people will start asking what you've been doing. Fair warning though: it hurts. Even with numbing cream, having a needle poke your face dozens of times is no joke. And don't schedule anything important that day — your face will be dotted with little red marks.
How it works
Rejuran Healer works by injecting polynucleotides (PN) derived from salmon DNA directly into your skin. These molecules act like a wake-up call to your skin cells — prompting them to produce collagen, rebuild elastin fibers, and pull in moisture on their own. The result is skin that heals and strengthens from the inside out, not just surface-level hydration.
Types
The original skin booster that injects polynucleotides (PN) from salmon DNA into the dermis. It activates fibroblasts to promote collagen and elastin regeneration. The standard protocol is 3–4 sessions spaced 2–4 weeks apart.
A lower-concentration, lower-viscosity version specifically designed for the delicate eye area. It can be safely injected into the thin, sensitive skin around the eyes.
A high-concentration, high-viscosity formulation specifically for scars. The thick gel acts as a physical scaffold under scar tissue, creating space for collagen to regenerate.
An upgraded version of Healer with added hyaluronic acid (HA) and lidocaine. The lidocaine drastically reduces pain, while the HA gives an immediate glow and hydration boost.
Doctor skill dependency
4/5Pain level
3/5It stings — a lot of tiny needle pricks across your whole face, even with numbing cream. The area under your eyes and around your mouth tends to be extra sensitive, so injections there can be more painful. Most people can tolerate it, but it's definitely not painless.
Not recommended for
Seafood or salmon allergy (the active ingredient is derived from salmon DNA — allergic reactions are possible) Keloid-prone skin (injection marks may scar abnormally) Active inflammation or breakouts on the skin Pregnant or breastfeeding
Procedure
A numbing cream is applied first, then a fine needle is used to inject the solution into the dermis at multiple points across the face. A full-face treatment can feel like 100+ tiny injections. You'll see small red dots all over your face when it's done — totally normal.
Ask JISOO anything about skin or clinics.